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B–N/B–H Transborylation: borane-catalysed nitrile hydroboration

The reduction of nitriles to primary amines is a useful transformation in organic synthesis, however, it often relies upon stoichiometric reagents or transition-metal catalysis. Herein, a borane-catalysed hydroboration of nitriles to give primary amines is reported. Good yields (48–95%) and chemosel...

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Detalles Bibliográficos
Autores principales: Meger, Filip, Kwok, Alexander C W, Gilch, Franziska, Willcox, Dominic R, Hendy, Alex J, Nicholson, Kieran, Bage, Andrew D, Langer, Thomas, Hunt, Thomas A, Thomas, Stephen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531558/
https://www.ncbi.nlm.nih.gov/pubmed/36247978
http://dx.doi.org/10.3762/bjoc.18.138