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Disease predisposition of human leukocyte antigen class II genes influences the gut microbiota composition in patients with primary biliary cholangitis

BACKGROUND: The human leukocyte antigen (HLA) susceptibility gene is the main genetic risk factor for primary biliary cholangitis (PBC). The prognosis of patients with PBC is linked to gut microbiota dysbiosis. However, whether the HLA alleles are associated with the gut microbiota distribution and...

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Detalles Bibliográficos
Autores principales: Huang, Chun-Yang, Zhang, Hai-Ping, Han, Wei-Jia, Zhao, Dan-Tong, Liao, Hui-Yu, Ma, Yin-Xue, Xu, Bin, Li, Li-Juan, Han, Ying, Liu, Xiu-Hong, Wang, Qi, Lou, Jin-Li, Zhang, Xiao-Dan, Zhao, Juan, Li, Wen-Juan, Liu, Yan-Min, Yan, Hui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531677/
https://www.ncbi.nlm.nih.gov/pubmed/36203614
http://dx.doi.org/10.3389/fimmu.2022.984697