Targeting ligand-dependent wnt pathway dysregulation in gastrointestinal cancers through porcupine inhibition

Gastrointestinal cancers are responsible for more cancer deaths than any other system of the body. This review summarises how Wnt pathway dysregulation contributes to the development of the most common gastrointestinal cancers, with a particular focus on the nature and frequency of upstream pathway...

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Detalles Bibliográficos
Autores principales: Flanagan, Dustin J., Woodcock, Simon A., Phillips, Caroline, Eagle, Catherine, Sansom, Owen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531712/
https://www.ncbi.nlm.nih.gov/pubmed/35358569
http://dx.doi.org/10.1016/j.pharmthera.2022.108179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531712/
https://www.ncbi.nlm.nih.gov/pubmed/35358569
http://dx.doi.org/10.1016/j.pharmthera.2022.108179

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