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Targeting ligand-dependent wnt pathway dysregulation in gastrointestinal cancers through porcupine inhibition
Gastrointestinal cancers are responsible for more cancer deaths than any other system of the body. This review summarises how Wnt pathway dysregulation contributes to the development of the most common gastrointestinal cancers, with a particular focus on the nature and frequency of upstream pathway...
Autores principales: | Flanagan, Dustin J., Woodcock, Simon A., Phillips, Caroline, Eagle, Catherine, Sansom, Owen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531712/ https://www.ncbi.nlm.nih.gov/pubmed/35358569 http://dx.doi.org/10.1016/j.pharmthera.2022.108179 |
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