Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini

Infection with the food-borne liver fluke Opisthorchis viverrini is the principal risk factor for cholangiocarcinoma (CCA) in the Mekong Basin countries of Thailand, Lao PDR, Vietnam, Myanmar and Cambodia. Using a novel model of CCA, involving infection with gene-edited liver flukes in the hamster d...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaiyadet, Sujittra, Tangkawattana, Sirikachorn, Smout, Michael J., Ittiprasert, Wannaporn, Mann, Victoria H., Deenonpoe, Raksawan, Arunsan, Patpicha, Loukas, Alex, Brindley, Paul J., Laha, Thewarach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531791/
https://www.ncbi.nlm.nih.gov/pubmed/36137145
http://dx.doi.org/10.1371/journal.ppat.1010839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531791/
https://www.ncbi.nlm.nih.gov/pubmed/36137145
http://dx.doi.org/10.1371/journal.ppat.1010839

Ejemplares similares