Unfolding and identification of membrane proteins in situ

Single-molecule force spectroscopy (SMFS) uses the cantilever tip of an atomic force microscope (AFM) to apply a force able to unfold a single protein. The obtained force-distance curve encodes the unfolding pathway, and from its analysis it is possible to characterize the folded domains. SMFS has b...

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Detalles Bibliográficos
Autores principales: Galvanetto, Nicola, Ye, Zhongjie, Marchesi, Arin, Mortal, Simone, Maity, Sourav, Laio, Alessandro, Torre, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531951/
https://www.ncbi.nlm.nih.gov/pubmed/36094473
http://dx.doi.org/10.7554/eLife.77427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531951/
https://www.ncbi.nlm.nih.gov/pubmed/36094473
http://dx.doi.org/10.7554/eLife.77427

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