Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer

Oxaliplatin is the main chemotherapy drug for gastric cancer (GC), but quite a few patients are resistant to oxaliplatin, which contributes to the poor prognosis of GC patients. There is therefore an urgent need to identify potential targets for reversing chemotherapy resistance in GC patients. In t...

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Detalles Bibliográficos
Autores principales: Tang, Xiaolong, Liang, Yahang, Sun, Guorui, He, Qingsi, Hou, Zhenyu, Jiang, Xingzhi, Gao, Peng, Qu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532395/
https://www.ncbi.nlm.nih.gov/pubmed/36195596
http://dx.doi.org/10.1038/s41419-022-05299-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532395/
https://www.ncbi.nlm.nih.gov/pubmed/36195596
http://dx.doi.org/10.1038/s41419-022-05299-2

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