The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase

TAPL is a lysosomal ATP-binding cassette transporter that translocates a broad spectrum of polypeptides from the cytoplasm into the lysosomal lumen. Here we report that, in addition to its well-known role as a peptide translocator, TAPL exhibits an ATP-dependent phosphatidylserine floppase activity...

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Detalles Bibliográficos
Autores principales: Park, Jun Gyou, Kim, Songwon, Jang, Eunhong, Choi, Seung Hun, Han, Hyunsu, Ju, Seulgi, Kim, Ji Won, Min, Da Sol, Jin, Mi Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532399/
https://www.ncbi.nlm.nih.gov/pubmed/36195619
http://dx.doi.org/10.1038/s41467-022-33593-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532399/
https://www.ncbi.nlm.nih.gov/pubmed/36195619
http://dx.doi.org/10.1038/s41467-022-33593-2

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