Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism

Perturbation of proteostasis triggers the adaptive responses that contribute to the homeostatic pro-survival response, whereas disruption of proteostasis can ultimately lead to cell death. Brain-specific oxysterol—i.e., 24(S)-hydroxycholesterol (24S-OHC)—has been shown to cause cytotoxicity when est...

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Detalles Bibliográficos
Autores principales: Urano, Yasuomi, Osaki, Shoya, Chiba, Ren, Noguchi, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532424/
https://www.ncbi.nlm.nih.gov/pubmed/36195595
http://dx.doi.org/10.1038/s41420-022-01197-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532424/
https://www.ncbi.nlm.nih.gov/pubmed/36195595
http://dx.doi.org/10.1038/s41420-022-01197-w

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