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Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism
Perturbation of proteostasis triggers the adaptive responses that contribute to the homeostatic pro-survival response, whereas disruption of proteostasis can ultimately lead to cell death. Brain-specific oxysterol—i.e., 24(S)-hydroxycholesterol (24S-OHC)—has been shown to cause cytotoxicity when est...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532424/ https://www.ncbi.nlm.nih.gov/pubmed/36195595 http://dx.doi.org/10.1038/s41420-022-01197-w |