Identification of distinct functional thymic programming of fetal and pediatric human γδ thymocytes via single-cell analysis

Developmental thymic waves of innate-like and adaptive-like γδ T cells have been described, but the current understanding of γδ T cell development is mainly limited to mouse models. Here, we combine single cell (sc) RNA gene expression and sc γδ T cell receptor (TCR) sequencing on fetal and pediatri...

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Detalles Bibliográficos
Autores principales: Sanchez Sanchez, Guillem, Papadopoulou, Maria, Azouz, Abdulkader, Tafesse, Yohannes, Mishra, Archita, Chan, Jerry K. Y., Fan, Yiping, Verdebout, Isoline, Porco, Silvana, Libert, Frédérick, Ginhoux, Florent, Vandekerckhove, Bart, Goriely, Stanislas, Vermijlen, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532436/
https://www.ncbi.nlm.nih.gov/pubmed/36195611
http://dx.doi.org/10.1038/s41467-022-33488-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532436/
https://www.ncbi.nlm.nih.gov/pubmed/36195611
http://dx.doi.org/10.1038/s41467-022-33488-2

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