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Schisandrol A protects AGEs-induced neuronal cells death by allosterically targeting ATP6V0d1 subunit of V-ATPase

Diabetes have been shown to cause progressive neuronal injury with pain and numbness via advanced glycation end-products (AGEs)-induced neuronal cell apoptosis; however, the valuable drug targets for diabetic neuropathy have been poorly reported so far. In this study, we discovered a natural small-m...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoqing, Zhao, Shaoyang, Liu, Tingting, Yao, Lu, Zhao, Meimei, Ye, Xiaoming, Zhang, Xiaowen, Guo, Qiang, Tu, Pengfei, Zeng, Kewu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532558/
https://www.ncbi.nlm.nih.gov/pubmed/36213534
http://dx.doi.org/10.1016/j.apsb.2022.06.013