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Schisandrol A protects AGEs-induced neuronal cells death by allosterically targeting ATP6V0d1 subunit of V-ATPase
Diabetes have been shown to cause progressive neuronal injury with pain and numbness via advanced glycation end-products (AGEs)-induced neuronal cell apoptosis; however, the valuable drug targets for diabetic neuropathy have been poorly reported so far. In this study, we discovered a natural small-m...
Autores principales: | Zhou, Xiaoqing, Zhao, Shaoyang, Liu, Tingting, Yao, Lu, Zhao, Meimei, Ye, Xiaoming, Zhang, Xiaowen, Guo, Qiang, Tu, Pengfei, Zeng, Kewu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532558/ https://www.ncbi.nlm.nih.gov/pubmed/36213534 http://dx.doi.org/10.1016/j.apsb.2022.06.013 |
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