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Gli1 promotes epithelial–mesenchymal transition and metastasis of non-small cell lung carcinoma by regulating snail transcriptional activity and stability

Metastasis is crucial for the mortality of non-small cell lung carcinoma (NSCLC) patients. The epithelial–mesenchymal transition (EMT) plays a critical role in regulating tumor metastasis. Glioma-associated oncogene 1 (Gli1) is aberrantly active in a series of tumor tissues. However, the molecular r...

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Detalles Bibliográficos
Autores principales: Lei, Xueping, Li, Zhan, Zhong, Yihang, Li, Songpei, Chen, Jiacong, Ke, Yuanyu, Lv, Sha, Huang, Lijuan, Pan, Qianrong, Zhao, Lixin, Yang, Xiangyu, Chen, Zisheng, Deng, Qiudi, Yu, Xiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532560/
https://www.ncbi.nlm.nih.gov/pubmed/36213531
http://dx.doi.org/10.1016/j.apsb.2022.05.024