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Autophagy and beyond: Unraveling the complexity of UNC-51-like kinase 1 (ULK1) from biological functions to therapeutic implications

UNC-51-like kinase 1 (ULK1), as a serine/threonine kinase, is an autophagic initiator in mammals and a homologous protein of autophagy related protein (Atg) 1 in yeast and of UNC-51 in Caenorhabditis elegans. ULK1 is well-known for autophagy activation, which is evolutionarily conserved in protein t...

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Detalles Bibliográficos
Autores principales: Zou, Ling, Liao, Minru, Zhen, Yongqi, Zhu, Shiou, Chen, Xiya, Zhang, Jin, Hao, Yue, Liu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532564/
https://www.ncbi.nlm.nih.gov/pubmed/36213540
http://dx.doi.org/10.1016/j.apsb.2022.06.004