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Characterizing the lipid fingerprint of the mechanosensitive channel Piezo2

Piezo2 is a mechanosensitive ion channel that plays critical roles in sensing touch and pain, proprioception, and regulation of heart rate. Global knockout of Piezo2 leads to perinatal lethality in mice, and Piezo2 gain-of-function mutations are associated with distal arthrogryposis, a disease chara...

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Detalles Bibliográficos
Autores principales: Lin, Yiechang, Buyan, Amanda, Corry, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532583/
https://www.ncbi.nlm.nih.gov/pubmed/35861699
http://dx.doi.org/10.1085/jgp.202113064