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FOXA1 regulates alternative splicing in prostate cancer

Dysregulation of alternative splicing in prostate cancer is linked to transcriptional programs activated by AR, ERG, FOXA1, and MYC. Here, we show that FOXA1 functions as the primary orchestrator of alternative splicing dysregulation across 500 primary and metastatic prostate cancer transcriptomes....

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Detalles Bibliográficos
Autores principales: Del Giudice, Marco, Foster, John G., Peirone, Serena, Rissone, Alberto, Caizzi, Livia, Gaudino, Federica, Parlato, Caterina, Anselmi, Francesca, Arkell, Rebecca, Guarrera, Simonetta, Oliviero, Salvatore, Basso, Giuseppe, Rajan, Prabhakar, Cereda, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532847/
https://www.ncbi.nlm.nih.gov/pubmed/36170835
http://dx.doi.org/10.1016/j.celrep.2022.111404