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Targeting upregulated RNA binding protein RCAN1.1: a promising strategy for neuroprotection in acute ischemic stroke

AIMS: To explore the expression changes and roles of the RNA‐binding protein RCAN1.1 in acute ischemic stroke (AIS), and to preliminarily confirm the medicinal value of the RNA aptamer R1SR13 in AIS by targeting RCAN1.1. METHODS: Two mouse AIS models of middle cerebral artery occlusion (MCAO) and ri...

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Detalles Bibliográficos
Autores principales: Yun, Yan, Yang, Xiaxin, Tan, Shichuan, Wang, Pin, Ji, Yanbin, Sun, Xiulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532900/
https://www.ncbi.nlm.nih.gov/pubmed/35900849
http://dx.doi.org/10.1111/cns.13921