Cargando…
Pronounced antiseizure activity of the subtype‐selective GABA(A) positive allosteric modulator darigabat in a mouse model of drug‐resistant focal epilepsy
AIM: Darigabat is an α2/3/5 subunit‐selective positive allosteric modulator of GABA(A) receptors that has demonstrated broad‐spectrum activity in several preclinical models of epilepsy as well as in a clinical photoepilepsy trial. The objective here was to assess the acute antiseizure effect of dari...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532903/ https://www.ncbi.nlm.nih.gov/pubmed/35965432 http://dx.doi.org/10.1111/cns.13927 |