Effects of α5 GABA(A) receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease

AIMS: GABAergic modulation involved in cognitive processing appears to be substantially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to assess if negative and positive allosteric modulators of α5 GABA(A) receptors (NAM and PAM, respectively) would affect soc...

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Detalles Bibliográficos
Autores principales: Aranđelović, Jovana, Santrač, Anja, Batinić, Bojan, Todorović, Lidija, Stevanović, Vladimir, Tiruveedhula, Veera Venkata Naga Phani Babu, Sharmin, Dishary, Rashid, Farjana, Stanojević, Boban, Cook, James M., Savić, Miroslav M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532908/
https://www.ncbi.nlm.nih.gov/pubmed/35822698
http://dx.doi.org/10.1111/cns.13914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532908/
https://www.ncbi.nlm.nih.gov/pubmed/35822698
http://dx.doi.org/10.1111/cns.13914

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