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Exploring glioblastoma stem cell heterogeneity: Immune microenvironment modulation and therapeutic opportunities
Despite its growing use in cancer treatment, immunotherapy has been virtually ineffective in clinical trials for gliomas. The inherently cold tumor immune microenvironment (TIME) in gliomas, characterized by a high ratio of pro-tumor to anti-tumor immune cell infiltrates, acts as a seemingly insurmo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532940/ https://www.ncbi.nlm.nih.gov/pubmed/36212415 http://dx.doi.org/10.3389/fonc.2022.995498 |