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AMPK phosphorylates NAMPT to regulate NAD(+) homeostasis under ionizing radiation

Radiation-induced oral mucositis is the most common complication for patients who receive head/neck radiotherapy. Nicotinamide adenine dinucleotide (NAD(+)) is vital for DNA damage repair under ionizing radiation, through functioning as either the substrate for protein poly(ADP-ribosyl)ation at DNA...

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Detalles Bibliográficos
Autores principales: Liao, Xiaoyu, Huang, Xiaoke, Li, Xin, Qiu, Xuemei, Li, Mi, Liu, Rui, He, Tao, Tang, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532994/
https://www.ncbi.nlm.nih.gov/pubmed/36196536
http://dx.doi.org/10.1098/rsob.220213