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AMPK phosphorylates NAMPT to regulate NAD(+) homeostasis under ionizing radiation
Radiation-induced oral mucositis is the most common complication for patients who receive head/neck radiotherapy. Nicotinamide adenine dinucleotide (NAD(+)) is vital for DNA damage repair under ionizing radiation, through functioning as either the substrate for protein poly(ADP-ribosyl)ation at DNA...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532994/ https://www.ncbi.nlm.nih.gov/pubmed/36196536 http://dx.doi.org/10.1098/rsob.220213 |