A Cancer Cell–Intrinsic GOT2–PPARδ Axis Suppresses Antitumor Immunity

Despite significant recent advances in precision medicine, pancreatic ductal adenocarcinoma (PDAC) remains near uniformly lethal. Although immune-modulatory therapies hold promise to meaningfully improve outcomes for patients with PDAC, the development of such therapies requires an improved understa...

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Detalles Bibliográficos
Autores principales: Abrego, Jaime, Sanford-Crane, Hannah, Oon, Chet, Xiao, Xu, Betts, Courtney B., Sun, Duanchen, Nagarajan, Shanthi, Diaz, Luis, Sandborg, Holly, Bhattacharyya, Sohinee, Xia, Zheng, Coussens, Lisa M., Tontonoz, Peter, Sherman, Mara H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533011/
https://www.ncbi.nlm.nih.gov/pubmed/35894778
http://dx.doi.org/10.1158/2159-8290.CD-22-0661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533011/
https://www.ncbi.nlm.nih.gov/pubmed/35894778
http://dx.doi.org/10.1158/2159-8290.CD-22-0661

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