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Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation

BACKGROUND: Colorectal cancer is related to ulcerative colitis. This study aimed to investigate the effects of aspirin on non-specific inflammation developing into cancer. METHODS: Ulcerative colitis model was generated by administrating azoxymethane/dextran sulfate sodium to mice. Weight, tumor siz...

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Detalles Bibliográficos
Autores principales: Chen, Yingying, Sun, Liying, Li, Dongyue, Yin, Xunhai, Shang, Guoyin, Diao, Tiantian, Shi, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish Society of Gastroenterology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533073/
https://www.ncbi.nlm.nih.gov/pubmed/35946886
http://dx.doi.org/10.5152/tjg.2022.21855