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Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability

AIMS: Exosomes (exo) are involved in the progression of osteoarthritis (OA). This study aimed to investigate the function of dysfunctional chondrocyte-derived exo (DC-exo) on OA in rats and rat macrophages. METHODS: Rat-derived chondrocytes were isolated, and DCs induced with interleukin (IL)-1β wer...

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Detalles Bibliográficos
Autores principales:	Lv, Guohua, Wang, Bing, Li, Lei, Li, Yunchao, Li, Xinyi, He, Haoyu, Kuang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2022
Materias:	Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533253/ https://www.ncbi.nlm.nih.gov/pubmed/36066338 http://dx.doi.org/10.1302/2046-3758.119.BJR-2021-0443.R2

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