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Analysis of the orientation of cholesterol in high-density lipoprotein nanodiscs using solid-state NMR

Cholesterol is an essential component of eukaryotic cellular membranes that regulates the order and phase behaviour of dynamic lipid bilayers. Although cholesterol performs many vital physiological roles, hypercholesterolaemia and the accumulation of cholesterol in atherosclerotic plaques can increa...

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Detalles Bibliográficos
Autores principales: Lau, Sophie, Middleton, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533372/
https://www.ncbi.nlm.nih.gov/pubmed/36134896
http://dx.doi.org/10.1039/d2cp02393h