Targeting the succinate receptor effectively inhibits periodontitis

Periodontal disease (PD) is one of the most common inflammatory diseases in humans and is initiated by an oral microbial dysbiosis that stimulates inflammation and bone loss. Here, we report an abnormal elevation of succinate in the subgingival plaque of subjects with severe PD. Succinate activates...

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Detalles Bibliográficos
Autores principales: Guo, Yuqi, Xu, Fangxi, Thomas, Scott C., Zhang, Yanli, Paul, Bidisha, Sakilam, Satish, Chae, Sungpil, Li, Patty, Almeter, Caleb, Kamer, Angela R., Arora, Paramjit, Graves, Dana T., Saxena, Deepak, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533417/
https://www.ncbi.nlm.nih.gov/pubmed/36130514
http://dx.doi.org/10.1016/j.celrep.2022.111389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533417/
https://www.ncbi.nlm.nih.gov/pubmed/36130514
http://dx.doi.org/10.1016/j.celrep.2022.111389

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