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Targeting the succinate receptor effectively inhibits periodontitis
Periodontal disease (PD) is one of the most common inflammatory diseases in humans and is initiated by an oral microbial dysbiosis that stimulates inflammation and bone loss. Here, we report an abnormal elevation of succinate in the subgingival plaque of subjects with severe PD. Succinate activates...
Autores principales: | Guo, Yuqi, Xu, Fangxi, Thomas, Scott C., Zhang, Yanli, Paul, Bidisha, Sakilam, Satish, Chae, Sungpil, Li, Patty, Almeter, Caleb, Kamer, Angela R., Arora, Paramjit, Graves, Dana T., Saxena, Deepak, Li, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533417/ https://www.ncbi.nlm.nih.gov/pubmed/36130514 http://dx.doi.org/10.1016/j.celrep.2022.111389 |
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