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A photoinduced transient activating strategy for late-stage chemoselective C(sp(3))–H trifluoromethylation of azines
The direct functionalization of C(sp(3))–H bonds is an ultimately ideal synthetic strategy with high atom economy and step efficiency. However, the direct trifluoromethylation of electron-deficient heteroaryl adjacent C(sp(3))–H bonds remains a formidable challenge. We have described a transient act...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533475/ https://www.ncbi.nlm.nih.gov/pubmed/36320576 http://dx.doi.org/10.1039/d2sc03989c |