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A photoinduced transient activating strategy for late-stage chemoselective C(sp(3))–H trifluoromethylation of azines

The direct functionalization of C(sp(3))–H bonds is an ultimately ideal synthetic strategy with high atom economy and step efficiency. However, the direct trifluoromethylation of electron-deficient heteroaryl adjacent C(sp(3))–H bonds remains a formidable challenge. We have described a transient act...

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Detalles Bibliográficos
Autores principales: Huang, Mengjun, Ma, Jiawei, Zou, Zhenlei, Li, Heyin, Liu, Jiyang, Kong, Lingyu, Pan, Yi, Zhang, Weigang, Liang, Yong, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533475/
https://www.ncbi.nlm.nih.gov/pubmed/36320576
http://dx.doi.org/10.1039/d2sc03989c