Efficient synthesis and replication of diverse sequence libraries composed of biostable nucleic acid analogues

Functional nucleic acids can be evolved in vitro using cycles of selection and amplification, starting from diverse-sequence libraries, which are typically restricted to natural or partially-modified polymer chemistries. Here, we describe the efficient DNA-templated synthesis and reverse transcripti...

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Detalles Bibliográficos
Autores principales: Hervey, John R. D., Freund, Niklas, Houlihan, Gillian, Dhaliwal, Gurpreet, Holliger, Philipp, Taylor, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533476/
https://www.ncbi.nlm.nih.gov/pubmed/36320888
http://dx.doi.org/10.1039/d2cb00035k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533476/
https://www.ncbi.nlm.nih.gov/pubmed/36320888
http://dx.doi.org/10.1039/d2cb00035k

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