Cargando…
Efficient synthesis and replication of diverse sequence libraries composed of biostable nucleic acid analogues
Functional nucleic acids can be evolved in vitro using cycles of selection and amplification, starting from diverse-sequence libraries, which are typically restricted to natural or partially-modified polymer chemistries. Here, we describe the efficient DNA-templated synthesis and reverse transcripti...
Autores principales: | Hervey, John R. D., Freund, Niklas, Houlihan, Gillian, Dhaliwal, Gurpreet, Holliger, Philipp, Taylor, Alexander I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533476/ https://www.ncbi.nlm.nih.gov/pubmed/36320888 http://dx.doi.org/10.1039/d2cb00035k |
Ejemplares similares
-
Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′‐5′ Linkages
por: Cozens, Christopher, et al.
Publicado: (2015) -
Modified nucleic acids: replication, evolution, and next-generation therapeutics
por: Duffy, Karen, et al.
Publicado: (2020) -
Exploring the Chemistry of Genetic Information Storage
and Propagation through Polymerase Engineering
por: Houlihan, Gillian, et al.
Publicado: (2017) -
Biostable ssDNA Aptamers Specific for Hodgkin Lymphoma
por: Parekh, Parag, et al.
Publicado: (2013) -
Introduction to the themed collection on XNA xeno-nucleic acids
por: Bong, Dennis, et al.
Publicado: (2022)