From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles

The design of completely synthetic proteins from first principles—de novo protein design—is challenging. This is because, despite recent advances in computational protein–structure prediction and design, we do not understand fully the sequence-to-structure relationships for protein folding, assembly...

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Detalles Bibliográficos
Autores principales: Naudin, Elise A., Albanese, Katherine I., Smith, Abigail J., Mylemans, Bram, Baker, Emily G., Weiner, Orion D., Andrews, David M., Tigue, Natalie, Savery, Nigel J., Woolfson, Derek N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533478/
https://www.ncbi.nlm.nih.gov/pubmed/36320580
http://dx.doi.org/10.1039/d2sc04479j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533478/
https://www.ncbi.nlm.nih.gov/pubmed/36320580
http://dx.doi.org/10.1039/d2sc04479j

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