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From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles
The design of completely synthetic proteins from first principles—de novo protein design—is challenging. This is because, despite recent advances in computational protein–structure prediction and design, we do not understand fully the sequence-to-structure relationships for protein folding, assembly...
Autores principales: | Naudin, Elise A., Albanese, Katherine I., Smith, Abigail J., Mylemans, Bram, Baker, Emily G., Weiner, Orion D., Andrews, David M., Tigue, Natalie, Savery, Nigel J., Woolfson, Derek N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533478/ https://www.ncbi.nlm.nih.gov/pubmed/36320580 http://dx.doi.org/10.1039/d2sc04479j |
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