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A base-catalyzed approach for the anti-Markovnikov hydration of styrene derivatives

The base-catalyzed addition of 1-cyclopropylethanol to styrene derivatives with an acidic reaction workup enables anti-Markovnikov hydration. The use of either catalytic organic superbase or crown ether-ligated inorganic base permits hydration of a wide variety of styrene derivatives, including elec...

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Detalles Bibliográficos
Autores principales: Pajk, Spencer P., Qi, Zisong, Sujansky, Stephen J., Bandar, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533481/
https://www.ncbi.nlm.nih.gov/pubmed/36320585
http://dx.doi.org/10.1039/d2sc02827a