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Flavokawain A is a natural inhibitor of PRMT5 in bladder cancer

BACKGROUND: Protein arginine methyltransferases (PRMTs) regulate protein biological activity by modulating arginine methylation in cancer and are increasingly recognized as potential drug targets. Inhibitors targeting PRMTs are currently in the early phases of clinical trials and more candidate drug...

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Detalles Bibliográficos
Autores principales: Liu, Shuangjie, Liu, Zhuonan, Piao, Chiyuan, Zhang, Zhe, Kong, Chuize, Yin, Lei, Liu, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533510/
https://www.ncbi.nlm.nih.gov/pubmed/36199122
http://dx.doi.org/10.1186/s13046-022-02500-4