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Müller cell degeneration and microglial dysfunction in the Alzheimer’s retina

Amyloid beta (Aβ) deposits in the retina of the Alzheimer’s disease (AD) eye may provide a useful diagnostic biomarker for AD. This study focused on the relationship of Aβ with macroglia and microglia, as these glial cells are hypothesized to play important roles in homeostasis and clearance of Aβ i...

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Detalles Bibliográficos
Autores principales: Xu, Qinyuan Alis, Boerkoel, Pierre, Hirsch-Reinshagen, Veronica, Mackenzie, Ian R., Hsiung, Ging-Yuek Robin, Charm, Geoffrey, To, Elliott F., Liu, Alice Q., Schwab, Katerina, Jiang, Kailun, Sarunic, Marinko, Beg, Mirza Faisal, Pham, Wellington, Cui, Jing, To, Eleanor, Lee, Sieun, Matsubara, Joanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533552/
https://www.ncbi.nlm.nih.gov/pubmed/36199154
http://dx.doi.org/10.1186/s40478-022-01448-y