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Lipopolysaccharide downregulates the expression of ZO-1 protein through the Akt pathway
BACKGROUND: Neonatal bacterial meningitis is a common neonatal disease with high morbidity, and can cause serious sequelae when left untreated. Escherichia coli is the common pathogen, and its endotoxin, lipopolysaccharide (LPS) can damage the endothelial cells, increasing the permeability of the bl...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533599/ https://www.ncbi.nlm.nih.gov/pubmed/36199030 http://dx.doi.org/10.1186/s12879-022-07752-1 |