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Lipopolysaccharide downregulates the expression of ZO-1 protein through the Akt pathway

BACKGROUND: Neonatal bacterial meningitis is a common neonatal disease with high morbidity, and can cause serious sequelae when left untreated. Escherichia coli is the common pathogen, and its endotoxin, lipopolysaccharide (LPS) can damage the endothelial cells, increasing the permeability of the bl...

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Detalles Bibliográficos
Autores principales: Zou, Peicen, Yang, Fan, Ding, Yijun, Zhang, Di, Liu, Ying, Zhang, Jinjing, Wu, Dan, Wang, Yajuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533599/
https://www.ncbi.nlm.nih.gov/pubmed/36199030
http://dx.doi.org/10.1186/s12879-022-07752-1