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Astroglial and microglial pathology in Down syndrome: Focus on Alzheimer's disease

Down syndrome (DS) arises from the triplication of human chromosome 21 and is considered the most common genetic cause of intellectual disability. Glial cells, specifically astroglia and microglia, display pathological alterations that might contribute to DS neuropathological alterations. Further, i...

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Detalles Bibliográficos
Autores principales: García, Octavio, Flores-Aguilar, Lisi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533652/
https://www.ncbi.nlm.nih.gov/pubmed/36212691
http://dx.doi.org/10.3389/fncel.2022.987212