Dapagliflozin induces apoptosis by downregulating cFILP(L) and increasing cFILP(S) instability in Caki-1 cells

Dapagliflozin is a sodium/glucose cotransporter 2 inhibitor used recently to treat patients with type 2 diabetes. A recent study has demonstrated that dapagliflozin induces apoptosis in human renal and breast tumor cells. However, to the best of our knowledge, the molecular mechanism underlying dapa...

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Detalles Bibliográficos
Autores principales: Jang, Ji Hoon, Lee, Tae-Jin, Sung, Eon-Gi, Song, In-Hwan, Kim, Joo-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533662/
https://www.ncbi.nlm.nih.gov/pubmed/36276495
http://dx.doi.org/10.3892/ol.2022.13521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533662/
https://www.ncbi.nlm.nih.gov/pubmed/36276495
http://dx.doi.org/10.3892/ol.2022.13521

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