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The antiviral drug telaprevir induces cell death by reducing FOXA1 expression in estrogen receptor α (ERα)‐positive breast cancer cells

Previously, we found that telaprevir (Tel), the inhibitor of hepatitis C virus NS3/4A serine protease, reduces estrogen receptor α (ERα) content at the transcriptional level without binding to the receptor, prevents ERα transcriptional activity, and inhibits basal and 17β‐estradiol (E2)‐dependent ce...

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Detalles Bibliográficos
Autores principales: Bartoloni, Stefania, Leone, Stefano, Pescatori, Sara, Cipolletti, Manuela, Acconcia, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533686/
https://www.ncbi.nlm.nih.gov/pubmed/36056637
http://dx.doi.org/10.1002/1878-0261.13303