Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis

In humans, germline TP53 mutations predispose carriers to a wide spectrum of cancers, which is known as Li–Fraumeni syndrome (LFS). To date, the association of melanomas with LFS remains unestablished. No melanomas have been reported in any P53‐modified mouse models either. In this study, we show th...

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Detalles Bibliográficos
Autores principales: Ran, Rensen, Li, Lanxin, Shi, Zhaoying, Liu, Guanghui, Jiang, Hao, Fang, Liangchen, Xu, Tingting, Huang, Jixuan, Chen, Weiqi, Chen, Yonglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533689/
https://www.ncbi.nlm.nih.gov/pubmed/35981147
http://dx.doi.org/10.1002/1878-0261.13301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533689/
https://www.ncbi.nlm.nih.gov/pubmed/35981147
http://dx.doi.org/10.1002/1878-0261.13301

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