Altered splicing of ATG16‐L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non‐small cell lung cancer

Despite the initial efficacy of using tyrosine kinase inhibitors of epidermal growth factor receptors (EGFR‐TKIs) for treating patients with non‐small cell lung cancer (NSCLC), resistance inevitably develops. Recent studies highlight a link between alternative splicing and cancer drug response. Ther...

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Detalles Bibliográficos
Autores principales: Hatat, Anne‐Sophie, Benoit‐Pilven, Clara, Pucciarelli, Amélie, de Fraipont, Florence, Lamothe, Lucie, Perron, Pascal, Rey, Amandine, Levra, Matteo Giaj, Toffart, Anne‐Claire, Auboeuf, Didier, Eymin, Beatrice, Gazzeri, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533692/
https://www.ncbi.nlm.nih.gov/pubmed/35593080
http://dx.doi.org/10.1002/1878-0261.13229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533692/
https://www.ncbi.nlm.nih.gov/pubmed/35593080
http://dx.doi.org/10.1002/1878-0261.13229

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