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Altered splicing of ATG16‐L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non‐small cell lung cancer
Despite the initial efficacy of using tyrosine kinase inhibitors of epidermal growth factor receptors (EGFR‐TKIs) for treating patients with non‐small cell lung cancer (NSCLC), resistance inevitably develops. Recent studies highlight a link between alternative splicing and cancer drug response. Ther...
Autores principales: | Hatat, Anne‐Sophie, Benoit‐Pilven, Clara, Pucciarelli, Amélie, de Fraipont, Florence, Lamothe, Lucie, Perron, Pascal, Rey, Amandine, Levra, Matteo Giaj, Toffart, Anne‐Claire, Auboeuf, Didier, Eymin, Beatrice, Gazzeri, Sylvie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533692/ https://www.ncbi.nlm.nih.gov/pubmed/35593080 http://dx.doi.org/10.1002/1878-0261.13229 |
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