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Diazepam leads to enhanced severity of orthopoxvirus infection and immune suppression

Benzodiazepines are drugs widely used as tranquilizers and in various other indications. We treated Balb/c mice with diazepam and infected them with cowpox (CPXV) and vaccinia virus (VACV). Disease index, weight loss and the antibody response were determined. Additionally the influence of different...

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Detalles Bibliográficos
Autores principales: Huemer, Hartwig P., Lassnig, Caroline, Nowotny, Norbert, Irschick, Eveline U., Kitchen, Maria, Pavlic, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533835/
https://www.ncbi.nlm.nih.gov/pubmed/20659521
http://dx.doi.org/10.1016/j.vaccine.2010.07.032