Use of live Variola virus to determine whether CAST/EiJ mice are a suitable surrogate animal model for human smallpox

Numerous animal models of systemic orthopoxvirus disease have been developed to evaluate therapeutics against variola virus (VARV), the causative agent of smallpox. These animal models do not resemble the disease presentation in human smallpox and most used surrogate Orthopoxviruses. A rodent model...

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Detalles Bibliográficos
Autores principales: Gallardo-Romero, Nadia F., Hutson, Christina L., Carroll, Darin, Kondas, Ashley V., Salzer, Johanna S., Dietz-Ostergaard, Sharon, Smith, Scott, Hudson, Paul, Olson, Victoria, Damon, Inger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533991/
https://www.ncbi.nlm.nih.gov/pubmed/31593747
http://dx.doi.org/10.1016/j.virusres.2019.197772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533991/
https://www.ncbi.nlm.nih.gov/pubmed/31593747
http://dx.doi.org/10.1016/j.virusres.2019.197772

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