GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer

Telomerase activation counteracts senescence and telomere erosion caused by uncontrolled proliferation. Epidermal growth factor receptor (EGFR) amplification drives proliferation while telomerase reverse transcriptase promoter (TERTp) mutations underlie telomerase reactivation through recruitment of...

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Detalles Bibliográficos
Autores principales: McKinney, Andrew M., Mathur, Radhika, Stevers, Nicholas O., Molinaro, Annette M., Chang, Susan M., Phillips, Joanna J., Costello, Joseph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534059/
https://www.ncbi.nlm.nih.gov/pubmed/36130485
http://dx.doi.org/10.1016/j.celrep.2022.111344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534059/
https://www.ncbi.nlm.nih.gov/pubmed/36130485
http://dx.doi.org/10.1016/j.celrep.2022.111344

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