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Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women

Physical distancing was used to prevent transmission of COVID-19, however there are concerns that this may promote harmful impacts on health, such as reduced levels of physical practice and changes in food intake and gut microbiota composition. This study evaluated the impacts of 6 months physical d...

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Autores principales: Longo, Priscila Larcher, de Aquino, Rita de Cassia, Ortiz, Sandra Regina Mota, de Oliveira, Roque Santos, Gavioli, Aline, do Amaral, Jônatas Bussador, Monteiro, Fernanda Rodrigues, de Almeida Franco, Raquel Riyuzo, Mereu, Giovana Rebonatti, Bachi, André Luis Lacerda, de Lima, Alexandre José Bancher, Laurentino, Gilberto Candido, Bastos, Marta Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534123/
https://www.ncbi.nlm.nih.gov/pubmed/36211483
http://dx.doi.org/10.3389/fnut.2022.972100
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author Longo, Priscila Larcher
de Aquino, Rita de Cassia
Ortiz, Sandra Regina Mota
de Oliveira, Roque Santos
Gavioli, Aline
do Amaral, Jônatas Bussador
Monteiro, Fernanda Rodrigues
de Almeida Franco, Raquel Riyuzo
Mereu, Giovana Rebonatti
Bachi, André Luis Lacerda
de Lima, Alexandre José Bancher
Laurentino, Gilberto Candido
Bastos, Marta Ferreira
author_facet Longo, Priscila Larcher
de Aquino, Rita de Cassia
Ortiz, Sandra Regina Mota
de Oliveira, Roque Santos
Gavioli, Aline
do Amaral, Jônatas Bussador
Monteiro, Fernanda Rodrigues
de Almeida Franco, Raquel Riyuzo
Mereu, Giovana Rebonatti
Bachi, André Luis Lacerda
de Lima, Alexandre José Bancher
Laurentino, Gilberto Candido
Bastos, Marta Ferreira
author_sort Longo, Priscila Larcher
collection PubMed
description Physical distancing was used to prevent transmission of COVID-19, however there are concerns that this may promote harmful impacts on health, such as reduced levels of physical practice and changes in food intake and gut microbiota composition. This study evaluated the impacts of 6 months physical distancing on Brazilian older women upon body mass index (BMI), strength, physical activity level (IPAQ), eating habits, neurological markers (brain-derived neurotrophic factor-BDNF and cortisol), cytokines (IL-2, IL-5, IL-6, IL-10, interferon-IFN-γ, tumor necrosis factor-TNF-α), aging-associated markers (vascular endothelial growth factor-VEGF, insulin-like growth factor-IGF-1, klotho and thymic stromal lymphopoietin-TSLP), besides specific groups of fecal microbiota. Fifteen women, over 60 years old, residents of São Paulo state (Brazil), were evaluated in March and in September 2020. The older adult women, with a mean age 66 ± 6.2 years presented significantly increased BMI and high effect size for non-protective foods consumption, reduced light physical activity and strength 6 months following the physical distancing. Furthermore, the serum concentration of IFN-γ, IGF-1, and IFN-γ/IL-5 were significantly higher, while lower concentration of IL-2 and IL-5 were observed 6 months after the physical distancing. Significant increase was noted only to Blautia spp. abundance after 6 months of physical distancing. Several correlations were observed at both before and after physical distancing, however, interestingly, many of them were lost or inverted 6 months following, while new ones emerged. Taken together, these results showed that lifestyle changes and stress conditions addressed by physical distancing from the COVID-19 pandemic impacted the health of older women included in the present study. Therefore, future follow-up studies are essential to propose interventions in order to restore the health conditions observed before the pandemic period, and thus to maintain the quality of life of older adults in different socioeconomic contexts.
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spelling pubmed-95341232022-10-06 Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women Longo, Priscila Larcher de Aquino, Rita de Cassia Ortiz, Sandra Regina Mota de Oliveira, Roque Santos Gavioli, Aline do Amaral, Jônatas Bussador Monteiro, Fernanda Rodrigues de Almeida Franco, Raquel Riyuzo Mereu, Giovana Rebonatti Bachi, André Luis Lacerda de Lima, Alexandre José Bancher Laurentino, Gilberto Candido Bastos, Marta Ferreira Front Nutr Nutrition Physical distancing was used to prevent transmission of COVID-19, however there are concerns that this may promote harmful impacts on health, such as reduced levels of physical practice and changes in food intake and gut microbiota composition. This study evaluated the impacts of 6 months physical distancing on Brazilian older women upon body mass index (BMI), strength, physical activity level (IPAQ), eating habits, neurological markers (brain-derived neurotrophic factor-BDNF and cortisol), cytokines (IL-2, IL-5, IL-6, IL-10, interferon-IFN-γ, tumor necrosis factor-TNF-α), aging-associated markers (vascular endothelial growth factor-VEGF, insulin-like growth factor-IGF-1, klotho and thymic stromal lymphopoietin-TSLP), besides specific groups of fecal microbiota. Fifteen women, over 60 years old, residents of São Paulo state (Brazil), were evaluated in March and in September 2020. The older adult women, with a mean age 66 ± 6.2 years presented significantly increased BMI and high effect size for non-protective foods consumption, reduced light physical activity and strength 6 months following the physical distancing. Furthermore, the serum concentration of IFN-γ, IGF-1, and IFN-γ/IL-5 were significantly higher, while lower concentration of IL-2 and IL-5 were observed 6 months after the physical distancing. Significant increase was noted only to Blautia spp. abundance after 6 months of physical distancing. Several correlations were observed at both before and after physical distancing, however, interestingly, many of them were lost or inverted 6 months following, while new ones emerged. Taken together, these results showed that lifestyle changes and stress conditions addressed by physical distancing from the COVID-19 pandemic impacted the health of older women included in the present study. Therefore, future follow-up studies are essential to propose interventions in order to restore the health conditions observed before the pandemic period, and thus to maintain the quality of life of older adults in different socioeconomic contexts. Frontiers Media S.A. 2022-09-14 /pmc/articles/PMC9534123/ /pubmed/36211483 http://dx.doi.org/10.3389/fnut.2022.972100 Text en Copyright © 2022 Longo, de Aquino, Ortiz, de Oliveira, Gavioli, do Amaral, Monteiro, de Almeida Franco, Mereu, Bachi, de Lima, Laurentino and Bastos. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Longo, Priscila Larcher
de Aquino, Rita de Cassia
Ortiz, Sandra Regina Mota
de Oliveira, Roque Santos
Gavioli, Aline
do Amaral, Jônatas Bussador
Monteiro, Fernanda Rodrigues
de Almeida Franco, Raquel Riyuzo
Mereu, Giovana Rebonatti
Bachi, André Luis Lacerda
de Lima, Alexandre José Bancher
Laurentino, Gilberto Candido
Bastos, Marta Ferreira
Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women
title Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women
title_full Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women
title_fullStr Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women
title_full_unstemmed Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women
title_short Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women
title_sort effects of physical distancing by covid-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of brazilian older women
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534123/
https://www.ncbi.nlm.nih.gov/pubmed/36211483
http://dx.doi.org/10.3389/fnut.2022.972100
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