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Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women
Physical distancing was used to prevent transmission of COVID-19, however there are concerns that this may promote harmful impacts on health, such as reduced levels of physical practice and changes in food intake and gut microbiota composition. This study evaluated the impacts of 6 months physical d...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534123/ https://www.ncbi.nlm.nih.gov/pubmed/36211483 http://dx.doi.org/10.3389/fnut.2022.972100 |
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author | Longo, Priscila Larcher de Aquino, Rita de Cassia Ortiz, Sandra Regina Mota de Oliveira, Roque Santos Gavioli, Aline do Amaral, Jônatas Bussador Monteiro, Fernanda Rodrigues de Almeida Franco, Raquel Riyuzo Mereu, Giovana Rebonatti Bachi, André Luis Lacerda de Lima, Alexandre José Bancher Laurentino, Gilberto Candido Bastos, Marta Ferreira |
author_facet | Longo, Priscila Larcher de Aquino, Rita de Cassia Ortiz, Sandra Regina Mota de Oliveira, Roque Santos Gavioli, Aline do Amaral, Jônatas Bussador Monteiro, Fernanda Rodrigues de Almeida Franco, Raquel Riyuzo Mereu, Giovana Rebonatti Bachi, André Luis Lacerda de Lima, Alexandre José Bancher Laurentino, Gilberto Candido Bastos, Marta Ferreira |
author_sort | Longo, Priscila Larcher |
collection | PubMed |
description | Physical distancing was used to prevent transmission of COVID-19, however there are concerns that this may promote harmful impacts on health, such as reduced levels of physical practice and changes in food intake and gut microbiota composition. This study evaluated the impacts of 6 months physical distancing on Brazilian older women upon body mass index (BMI), strength, physical activity level (IPAQ), eating habits, neurological markers (brain-derived neurotrophic factor-BDNF and cortisol), cytokines (IL-2, IL-5, IL-6, IL-10, interferon-IFN-γ, tumor necrosis factor-TNF-α), aging-associated markers (vascular endothelial growth factor-VEGF, insulin-like growth factor-IGF-1, klotho and thymic stromal lymphopoietin-TSLP), besides specific groups of fecal microbiota. Fifteen women, over 60 years old, residents of São Paulo state (Brazil), were evaluated in March and in September 2020. The older adult women, with a mean age 66 ± 6.2 years presented significantly increased BMI and high effect size for non-protective foods consumption, reduced light physical activity and strength 6 months following the physical distancing. Furthermore, the serum concentration of IFN-γ, IGF-1, and IFN-γ/IL-5 were significantly higher, while lower concentration of IL-2 and IL-5 were observed 6 months after the physical distancing. Significant increase was noted only to Blautia spp. abundance after 6 months of physical distancing. Several correlations were observed at both before and after physical distancing, however, interestingly, many of them were lost or inverted 6 months following, while new ones emerged. Taken together, these results showed that lifestyle changes and stress conditions addressed by physical distancing from the COVID-19 pandemic impacted the health of older women included in the present study. Therefore, future follow-up studies are essential to propose interventions in order to restore the health conditions observed before the pandemic period, and thus to maintain the quality of life of older adults in different socioeconomic contexts. |
format | Online Article Text |
id | pubmed-9534123 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95341232022-10-06 Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women Longo, Priscila Larcher de Aquino, Rita de Cassia Ortiz, Sandra Regina Mota de Oliveira, Roque Santos Gavioli, Aline do Amaral, Jônatas Bussador Monteiro, Fernanda Rodrigues de Almeida Franco, Raquel Riyuzo Mereu, Giovana Rebonatti Bachi, André Luis Lacerda de Lima, Alexandre José Bancher Laurentino, Gilberto Candido Bastos, Marta Ferreira Front Nutr Nutrition Physical distancing was used to prevent transmission of COVID-19, however there are concerns that this may promote harmful impacts on health, such as reduced levels of physical practice and changes in food intake and gut microbiota composition. This study evaluated the impacts of 6 months physical distancing on Brazilian older women upon body mass index (BMI), strength, physical activity level (IPAQ), eating habits, neurological markers (brain-derived neurotrophic factor-BDNF and cortisol), cytokines (IL-2, IL-5, IL-6, IL-10, interferon-IFN-γ, tumor necrosis factor-TNF-α), aging-associated markers (vascular endothelial growth factor-VEGF, insulin-like growth factor-IGF-1, klotho and thymic stromal lymphopoietin-TSLP), besides specific groups of fecal microbiota. Fifteen women, over 60 years old, residents of São Paulo state (Brazil), were evaluated in March and in September 2020. The older adult women, with a mean age 66 ± 6.2 years presented significantly increased BMI and high effect size for non-protective foods consumption, reduced light physical activity and strength 6 months following the physical distancing. Furthermore, the serum concentration of IFN-γ, IGF-1, and IFN-γ/IL-5 were significantly higher, while lower concentration of IL-2 and IL-5 were observed 6 months after the physical distancing. Significant increase was noted only to Blautia spp. abundance after 6 months of physical distancing. Several correlations were observed at both before and after physical distancing, however, interestingly, many of them were lost or inverted 6 months following, while new ones emerged. Taken together, these results showed that lifestyle changes and stress conditions addressed by physical distancing from the COVID-19 pandemic impacted the health of older women included in the present study. Therefore, future follow-up studies are essential to propose interventions in order to restore the health conditions observed before the pandemic period, and thus to maintain the quality of life of older adults in different socioeconomic contexts. Frontiers Media S.A. 2022-09-14 /pmc/articles/PMC9534123/ /pubmed/36211483 http://dx.doi.org/10.3389/fnut.2022.972100 Text en Copyright © 2022 Longo, de Aquino, Ortiz, de Oliveira, Gavioli, do Amaral, Monteiro, de Almeida Franco, Mereu, Bachi, de Lima, Laurentino and Bastos. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Nutrition Longo, Priscila Larcher de Aquino, Rita de Cassia Ortiz, Sandra Regina Mota de Oliveira, Roque Santos Gavioli, Aline do Amaral, Jônatas Bussador Monteiro, Fernanda Rodrigues de Almeida Franco, Raquel Riyuzo Mereu, Giovana Rebonatti Bachi, André Luis Lacerda de Lima, Alexandre José Bancher Laurentino, Gilberto Candido Bastos, Marta Ferreira Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women |
title | Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women |
title_full | Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women |
title_fullStr | Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women |
title_full_unstemmed | Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women |
title_short | Effects of physical distancing by COVID-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of Brazilian older women |
title_sort | effects of physical distancing by covid-19 pandemic on diet quality, neurological and immunological markers, and fecal microbiota of brazilian older women |
topic | Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534123/ https://www.ncbi.nlm.nih.gov/pubmed/36211483 http://dx.doi.org/10.3389/fnut.2022.972100 |
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