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Inhibition of the integrated stress response reverses oxidative stress damage-induced postoperative cognitive dysfunction

Postoperative cognitive dysfunction (POCD) is a common complication following anesthesia and surgery that might lead to a decline in learning and memory. Oxidative stress damage is one of the pathogenic mechanisms underlying POCD. Recent studies had shown that the integrated stress response (ISR) is...

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Detalles Bibliográficos
Autores principales: Jiang, Linhao, Dong, Rui, Xu, Minhui, Liu, Yujia, Xu, Jiyan, Ma, Zhengliang, Xia, Tianjiao, Gu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534309/
https://www.ncbi.nlm.nih.gov/pubmed/36212697
http://dx.doi.org/10.3389/fncel.2022.992869