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Blocking LAIR1 signaling in immune cells inhibits tumor development

The current immune checkpoint blockade therapy has been successful in treating some cancers but not others. New molecular targets and therapeutic approaches of cancer immunology need to be identified. Leukocyte associated immunoglobulin like receptor 1 (LAIR1) is an immune inhibitory receptor expres...

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Detalles Bibliográficos
Autores principales: Xie, Jingjing, Gui, Xun, Deng, Mi, Chen, Heyu, Chen, Yuanzhi, Liu, Xiaoye, Ku, Zhiqiang, Tan, Lingxiao, Huang, Ryan, He, Yubo, Zhang, Bruce, Lewis, Cheryl, Chen, Kenian, Xu, Lin, Xu, Jian, Huang, Tao, Liao, X. Charlene, Zhang, Ningyan, An, Zhiqiang, Zhang, Cheng Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534319/
https://www.ncbi.nlm.nih.gov/pubmed/36211388
http://dx.doi.org/10.3389/fimmu.2022.996026